The first successful kidney transplantation was performed by Dr. Joseph E. Murray at Harvard in 1954 in the world. Dr. Murray overcame the problem of histoincompatibility being a problem for kidney transplantation for the first time by kidney transplantation between maternal twins. Ronald, the twin sister of Richard Herrick helped him being about to dying due to renal failure and allowed Dr. Murray transplant a kidney to her brother. The place of Richard Herrick among kidney donors is very different. He is a leader making a history by donating his kidney to his sister in a world full of questions and unknown cases. His sister died 8 years after the transplantation.
Dr. Murray was deemed worthy of Nobel medicine prize for his success in 1990. Dr. Murray gave the light to hundreds of thousand kidney patients in the world waiting without hope thanks to this discovery making him win Nobel Prize. Thus, renal failure was incorporated into the group of diseases dominated by human after Dr. Murray performed the first successful kidney transplantation and developments increased more and more.
The most significant barrier for the kidney transplantation is the immune system of the recipient. Immune system accepting the kidney transplanted as a foreign object tries to reject this new tissue. Organ rejection has been controlled significantly by means of cortisone and other immunosuppressive medicines.
The first kidney transplantation in Turkey was realized by Dr. Mehmet Haberal on 3rd November 1975 at Hacettepe University by transplanting the kidney to the son donated by the mother. The first kidney transplantation from cadaver was realized by the same team by transplanting a cadaver kidney from Germany to a Turkish young.
The formal opinion of T.R directorate of religious affairs that organ transplantation is permissible religiously was announced on 6th March 1980.